Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Shh  sonic hedgehog   (Synonyms: Hhg1)
Results	Reference
1	J:210838 Adolphe C, Nieuwenhuis E, Villani R, Li ZJ, Kaur P, Hui CC, Wainwright BJ, Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation. J Invest Dermatol. 2014 Jul;134(7):1981-90
1	J:225216 Alvarez-Saavedra M, De Repentigny Y, Lagali PS, Raghu Ram EV, Yan K, Hashem E, Ivanochko D, Huh MS, Yang D, Mears AJ, Todd MA, Corcoran CP, Bassett EA, Tokarew NJ, Kokavec J, Majumder R, Ioshikhes I, Wallace VA, Kothary R, Meshorer E, Stopka T, Skoultchi AI, Picketts DJ, Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. Nat Commun. 2014;5:4181
1	J:149988 Beites CL, Hollenbeck PL, Kim J, Lovell-Badge R, Lander AD, Calof AL, Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue. Development. 2009 Jul;136(13):2187-97
1	J:184926 Blackburn J, Ohazama A, Kawasaki K, Otsuka-Tanaka Y, Liu B, Honda K, Rountree RB, Hu Y, Kawasaki M, Birchmeier W, Schmidt-Ullrich R, Kinoshita A, Schutte BC, Hammond NL, Dixon MJ, Sharpe PT, The role of Irf6 in tooth epithelial invagination. Dev Biol. 2012 May 1;365(1):61-70
1*	J:108509 Blaess S, Corrales JD, Joyner AL, Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region. Development. 2006 May;133(9):1799-809
1	J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801
1	J:137314 Buchtova M, Handrigan GR, Tucker AS, Lozanoff S, Town L, Fu K, Diewert VM, Wicking C, Richman JM, Initiation and patterning of the snake dentition are dependent on Sonic hedgehog signaling. Dev Biol. 2008 Jul 1;319(1):132-45
1	J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31;
1	J:161400 Carney RS, Mangin JM, Hayes L, Mansfield K, Sousa VH, Fishell G, Machold RP, Ahn S, Gallo V, Corbin JG, Sonic hedgehog expressing and responding cells generate neuronal diversity in the medial amygdala. Neural Dev. 2010;5:14
1	J:245758 Carreno G, Apps JR, Lodge EJ, Panousopoulos L, Haston S, Gonzalez-Meljem JM, Hahn H, Andoniadou CL, Martinez-Barbera JP, Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors. Development. 2017 Sep 15;144(18):3289-3302
1	J:94461 Corrales JD, Rocco GL, Blaess S, Guo Q, Joyner AL, Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development. 2004 Nov;131(22):5581-90
1	J:83530 Dakubo GD, Wang YP, Mazerolle C, Campsall K, McMahon AP, Wallace VA, Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development. 2003 Jul;130(13):2967-80
1	J:244957 El Shahawy M, Reibring CG, Neben CL, Hallberg K, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A, Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. PLoS Genet. 2017 Jul;13(7):e1006914
1*	J:132568 Glotzer DJ, Zelzer E, Olsen BR, Impaired skin and hair follicle development in Runx2 deficient mice. Dev Biol. 2008 Mar 15;315(2):459-73
1*	J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:237535 Haugas M, Tikker L, Achim K, Salminen M, Partanen J, Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Development. 2016 Dec 01;143(23):4495-4508
1*	J:213614 Hirata-Fukae C, Hirata T, The zinc finger gene Fezf2 is required for the development of excitatory neurons in the basolateral complex of the amygdala. Dev Dyn. 2014 Aug;243(8):1030-6
1	J:152851 Huang X, Ketova T, Fleming JT, Wang H, Dey SK, Litingtung Y, Chiang C, Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus. Development. 2009 Aug;136(15):2535-43
1	J:119729 Iwatsuki K, Liu HX, Gronder A, Singer MA, Lane TF, Grosschedl R, Mistretta CM, Margolskee RF, Wnt signaling interacts with Shh to regulate taste papilla development. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2253-8
1*	J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64
1	J:135131 Kashiwagi M, Morgan BA, Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007 Apr;134(8):1571-82
1*	J:260416 Kibe K, Nakatomi M, Kataoka S, Toyono T, Seta Y, Hey1 and Hey2 are differently expressed during mouse tooth development. Gene Expr Patterns. 2018 Jan;27:99-105
1	J:168981 Kim JJ, Gill PS, Rotin L, van Eede M, Henkelman RM, Hui CC, Rosenblum ND, Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis via GLI3 Repressor. J Neurosci. 2011 Feb 2;31(5):1825-36
1	J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670
1	J:189074 Li ZJ, Nieuwenhuis E, Nien W, Zhang X, Zhang J, Puviindran V, Wainwright BJ, Kim PC, Hui CC, Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis. Development. 2012 Nov;139(22):4152-61
1	J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124
1	J:126364 Merchan P, Bribian A, Sanchez-Camacho C, Lezameta M, Bovolenta P, de Castro F, Sonic hedgehog promotes the migration and proliferation of optic nerve oligodendrocyte precursors. Mol Cell Neurosci. 2007 Nov;36(3):355-368
1	J:81295 Mill P, Mo R, Fu H, Grachtchouk M, Kim PC, Dlugosz AA, Hui CC, Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes Dev. 2003 Jan 15;17(2):282-94
1	J:100687 Mill P, Mo R, Hu MC, Dagnino L, Rosenblum ND, Hui CC, Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Dev Cell. 2005 Aug;9(2):293-303
1	J:112169 Nieuwenhuis E, Motoyama J, Barnfield PC, Yoshikawa Y, Zhang X, Mo R, Crackower MA, Hui CC, Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia. Mol Cell Biol. 2006 Sep;26(17):6609-22
1	J:167091 Nyeng P, Bjerke MA, Norgaard GA, Qu X, Kobberup S, Jensen J, Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche. Dev Biol. 2011 Jan 1;349(1):20-34
1	J:62158 Ramalho-Santos M, Melton DA, McMahon AP, Hedgehog signals regulate multiple aspects of gastrointestinal development. Development. 2000 Jun;127(12):2763-72
1	J:196582 Romand R, Krezel W, Beraneck M, Cammas L, Fraulob V, Messaddeq N, Kessler P, Hashino E, Dolle P, Retinoic acid deficiency impairs the vestibular function. J Neurosci. 2013 Mar 27;33(13):5856-66
1	J:50050 St-Jacques B, Dassule HR, Karavanova I, Botchkarev VA, Li J, Danielian PS, McMahon JA, Lewis PM, Paus R, McMahon AP, Sonic hedgehog signaling is essential for hair development. Curr Biol. 1998 Sep 24;8(19):1058-68
1	J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72
1	J:161718 Suzuki Y, Ikeda K, Kawakami K, Regulatory role of Six1 in the development of taste papillae. Cell Tissue Res. 2010 Mar;339(3):513-25
1	J:288236 Takahashi M, Ikeda K, Ohmuraya M, Nakagawa Y, Sakuma T, Yamamoto T, Kawakami K, Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors. Dev Dyn. 2020 Apr 3;
1	J:204446 Tateya T, Imayoshi I, Tateya I, Hamaguchi K, Torii H, Ito J, Kageyama R, Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea. Development. 2013 Sep;140(18):3848-57
1*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:149542 Wang XP, O'Connell DJ, Lund JJ, Saadi I, Kuraguchi M, Turbe-Doan A, Cavallesco R, Kim H, Park PJ, Harada H, Kucherlapati R, Maas RL, Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood. Development. 2009 Jun;136(11):1939-49
1	J:78708 Wang YP, Dakubo G, Howley P, Campsall KD, Mazarolle CJ, Shiga SA, Lewis PM, McMahon AP, Wallace VA, Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells. Nat Neurosci. 2002 Sep;5(9):831-2
1	J:83385 Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ, JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure. Genes Dev. 2003 May 15;17(10):1271-80
1	J:173529 Yu T, Yaguchi Y, Echevarria D, Martinez S, Basson MA, Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum. Development. 2011 Jul;138(14):2957-68
1	J:145904 Zhang Z, Lan Y, Chai Y, Jiang R, Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row. Science. 2009 Feb 27;323(5918):1232-4